{"componentChunkName":"component---src-components-templates-announcement-js","path":"/announcements/st-jude-cloud-paper/","result":{"data":{"mdx":{"body":"function _extends() { _extends = Object.assign || function (target) { for (var i = 1; i < arguments.length; i++) { var source = arguments[i]; for (var key in source) { if (Object.prototype.hasOwnProperty.call(source, key)) { target[key] = source[key]; } } } return target; }; return _extends.apply(this, arguments); }\n\nfunction _objectWithoutProperties(source, excluded) { if (source == null) return {}; var target = _objectWithoutPropertiesLoose(source, excluded); var key, i; if (Object.getOwnPropertySymbols) { var sourceSymbolKeys = Object.getOwnPropertySymbols(source); for (i = 0; i < sourceSymbolKeys.length; i++) { key = sourceSymbolKeys[i]; if (excluded.indexOf(key) >= 0) continue; if (!Object.prototype.propertyIsEnumerable.call(source, key)) continue; target[key] = source[key]; } } return target; }\n\nfunction _objectWithoutPropertiesLoose(source, excluded) { if (source == null) return {}; var target = {}; var sourceKeys = Object.keys(source); var key, i; for (i = 0; i < sourceKeys.length; i++) { key = sourceKeys[i]; if (excluded.indexOf(key) >= 0) continue; target[key] = source[key]; } return target; }\n\n/* @jsx mdx */\nvar _frontmatter = {\n  \"title\": \"St. Jude Cloud Paper\",\n  \"date\": \"2021-01-06T00:00:00.000Z\",\n  \"template\": \"announcement\",\n  \"heroImage\": \"SJC-Paper-Header@2x.png\"\n};\n\nvar makeShortcode = function makeShortcode(name) {\n  return function MDXDefaultShortcode(props) {\n    console.warn(\"Component \" + name + \" was not imported, exported, or provided by MDXProvider as global scope\");\n    return mdx(\"div\", props);\n  };\n};\n\nvar DGLVButton = makeShortcode(\"DGLVButton\");\nvar FacebookPixel = makeShortcode(\"FacebookPixel\");\nvar DGLVPixel = makeShortcode(\"DGLVPixel\");\nvar MDXLayout = \"wrapper\";\nreturn function MDXContent(_ref) {\n  var components = _ref.components,\n      props = _objectWithoutProperties(_ref, [\"components\"]);\n\n  return mdx(MDXLayout, _extends({}, props, {\n    components: components,\n    mdxType: \"MDXLayout\"\n  }), mdx(\"h6\", {\n    className: \"text-muted\"\n  }, mdx(\"small\", null, mdx(\"strong\", null, mdx(\"p\", null, \"January 6, 2021\")))), mdx(\"h2\", {\n    className: \"border-bottom pb-4 pr-4 mb-4\"\n  }, mdx(\"p\", null, \"Genomic Data-Sharing Ecosystem for\\nthe Precision Medicine Era\")), mdx(\"h4\", {\n    className: \"pty-2 pb-3 text-muted\"\n  }, mdx(\"p\", null, \"St. Jude Children\\u2019s Research Hospital\\ncreated the largest cloud-based genomic resource for pediatric cancer and a\\ndata-sharing model to accelerate life-saving research.\")), mdx(\"hr\", null), mdx(\"p\", null, \"St. Jude Cloud is the largest cloud-based genomic data resource for pediatric\\ncancer, growing to host over 1.25 petabytes of genomic data available for\\nresearchers since its launch just a few years ago. But it's not just the\\ngenomics data that has grown. The site now hosts suites of analysis and\\nvisualization tools that accelerate research by allowing users to bypass\\nanalyzing the raw data from scratch.\"), mdx(DGLVButton, {\n    id: \"3c6f72\",\n    href: \"https://cancerdiscovery.aacrjournals.org/content/early/2021/01/05/2159-8290.CD-20-1230\",\n    className: \"btn btn-primary btn-lg mt-4 mb-5\",\n    buttonText: 'View Paper',\n    faIcon: faFileAlt,\n    faIconStyle: {\n      marginLeft: '10px'\n    },\n    mdxType: \"DGLVButton\"\n  }), mdx(\"h3\", null, \"Key Findings\"), mdx(\"br\", null), mdx(\"ul\", null, mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"St. Jude Cloud launched in April 2018 as a cloud-based, genomic data-sharing\\nplatform to improve diagnosis, treatment and outcomes for young cancer patients.\\nSt. Jude scientists developed the platform in collaboration with Microsoft and\\nDNAnexus.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"St. Jude Cloud has since grown enormously in size, scope and function. Today,\\nthe platform is a data-sharing ecosystem for accessing, analyzing and\\nvisualizing genomic data from childhood cancer patients and survivors as well as\\nchildren with sickle cell disease.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"St. Jude Cloud is the largest cloud-based, genomic data resource for pediatric\\ncancer. The platform offers 1.25 petabytes of harmonized genomic data, enough\\ndata to fill storage available on about 4,900 laptop computers.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"St. Jude Cloud currently includes more than 12,104 whole genomes, 7,697 whole\\nexomes and 2,202 transcriptomes. At its launch, St. Jude Cloud included more\\nthan 5,000 whole genomes and whole exomes and 1,200 transcriptomes.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"Additional genomic data from the St. Jude clinical genomics program are added\\nregularly, including curated, but unpublished data. The goal is to accelerate\\nresearch by making data more quickly available to the scientific community. This\\nis particularly important in pediatric cancer research, where more than half of\\ncases involve rare cancer subtypes, which makes the work more challenging.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"St. Jude Cloud data are available at no cost to researchers worldwide. The\\nsite attracts about 10,000 unique users per month.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"The platform includes three interconnected apps designed to make the site user\\nfriendly to investigators without formal computational training. Here are the\\napps:\", mdx(\"ul\", {\n    \"parentName\": \"li\"\n  }, mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"Genomics Platform provides registered users with access to harmonized raw\\ndata plus end-to-end genomic analysis, some using innovative algorithms St.\\nJude scientists developed that allow for integrated St. Jude Cloud data\\nanalysis.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"Pediatric Cancer Knowledgebase (PeCan) enables exploration of published data\\ncontributed by the global research community on acquired (somatic) cancer\\ngenomic variations in more than 5,000 pediatric patients.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"Visualization Community also allows all users to explore user data along\\nwith the published data using interactive maps and visualization tools St.\\nJude scientists developed. The tools give researchers a more integrated view\\nof childhood cancer data, including genomic and epigenomic data plus clinical\\ninformation.\"))), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"St. Jude Cloud was created as a resource and model of federated data-sharing\\nfor the global research community.\"), mdx(\"li\", {\n    \"parentName\": \"ul\"\n  }, \"The publication comes amid ongoing initiatives among researchers,\\ninstitutions, organizations and government agencies about how to enhance\\npediatric cancer data sharing.\")), mdx(FacebookPixel, {\n    id: 303977603413490,\n    events: ['ViewContent'],\n    mdxType: \"FacebookPixel\"\n  }), mdx(DGLVPixel, {\n    id: '3c6f72',\n    mdxType: \"DGLVPixel\"\n  }));\n}\n;\nMDXContent.isMDXComponent = true;","frontmatter":{"heroImage":"SJC-Paper-Header@2x.png","title":"St. Jude Cloud Paper"}}},"pageContext":{"slug":"announcements/st-jude-cloud-paper/"}},"staticQueryHashes":["2320597721","63159454"]}